Enfoque conservador en paciente con múltiples lesiones periapicales radiolúcidas: Abordaje combinado endodóntico-quirúrgico / Conservative approach in a patient with multiple radiolucent periapical lesions: Combined endodontic-surgical access

Se presenta el caso de un paciente varón de 43 años con lesiones periapicales radiolúcidas de origen endodóntico en dientes pilares de rehabilitación fija metalocerámica, que acude a consulta para valorar la posibilidad de mantener sus dientes. Tras la exploración clínica y radiológica mediante radiografías periapicales y tomografía computerizada de haz cónico (CBCT) se decide realizar un abordaje combinado endodóntico-quirúrgico. La evolución clínica fue favorable y los controles radiográficos y tomográficos mostraron la resolución de las lesiones radiolúcidas preexistentes. El retratamiento endodóntico combinado con la microcirugía periapical son herramientas eficaces en el tratamiento conservador de dientes con lesiones periapicales de origen endodóntico

In this case report, we present a 43-year old male patient with multiple periapical radiolucent lesions caused by endodontic failure in teeth supporting a metalloceramic prosthetic rehabilitation, who came to the office asking for any possibility to maintain his teeth. After clinical and radiological exploration with periapical x-rays and cone beam computer tomography (CBCT), we decided to use a combined endodontic-surgical approach. Clinical evolution was favourable, and radiologica - tomographic controls showed complete healing of periapical radiolucent lesions. Endodontic retreatment combined with periapical microsurgery are effective tools for conservative treatment in teeth with periapical lesions caused by endodontic failures

La utilización de pilares transmucosos definitivos de colocación inmediata / The use of immediate placement of definitive transmucosal abutments

El uso de pilares de cicatrización transmucosos previos a la colocación del pilar protésico definitivo es una técnica que se ha desarrollado durante muchos años en la implantología clásica. La desconexión y conexión de forma repetida de estos pilares o aditamentos dan lugar a una respuesta ósea negativa que se manifiesta en forma de pérdida de hueso a nivel de la cresta marginal, acompañada por una migración apical de tejidos blandos. Este artículo pretende realizar una revisión de la literatura del estado actual del uso de los pilares transmucosos definitivos con colocación inmediata el día de la inserción de los implantes y el mantenimiento del sellado biológico, minimizando la pérdida ósea periimplantaria y remodelando de forma adecuada los tejidos blandos adyacentes, frente al protocolo tradiciónal del uso de aditamentos que se desconectan en multiples ocasiones produciendo pérdida ósea periimplantaria. La evidencia científica sugiere que los mejores resultados biológicos, estéticos y funciónales se consiguen con el uso del pilar definitivo colocado de forma inmediata a la inserción del implante, especialmente en implantes colocados de forma yuxtacrestal y en implantes postextracción

The use of transmucosal healing abutments before the placement of the definitive prosthetic abutment is a technique that has been developed for many years in classical implantology. Repeated disconnection and connection of theses abutments result in a negative bone response that manifests as bone loss at the marginal ridge level, accompanied by apical soft tissue migration. This article aims to review the current status in the scientific literature of the use of the definitive transepithelial abutments with immediate placement on the day of implant insertion and maintenance of the biological seal, minimizing peri-implant bone loss and adequately remodeling the adjacent soft tissues, compared to the traditional protocol of the use of abutments that are disconnected on multiple occasions producing peri-implant bone loss. Scientific evidence suggests that the best biological, aesthetic, and functional results are achieved with the use of the definitive abutment placed immediately after implant insertion, especially in yuxtacrestal implants and post-extraction implants

Periapical implant lesion: A systematic review

Purpose: The aim of this study was to systematically review the evidence for periapical implant lesion, which makes a patient more susceptible to the periapical lesion, frequency, symptoms, signs (including radiological findings) and possible treatment options. Material and Methods: A systematic literature review and analysis of publications included in PubMed, Embase and Cochrane; articles published until March 2016; with a populations, exposures and outcomes (PEO) search strategy was performed, focused on the issue: 'In patients with periapical lesion to the implant during the osseointegration, what symptoms, signs, and changes in complementary examination manifested, for according to that stage, be intervened with the appropriate approach? '. The set criteria for inclusion were peer-reviewed articles. Results: From a total of 212 papers identified, 36 studies were included in this systematic review, with 15461 implants evaluated and 183 periapical implant lesions. Which 8 papers included more than 5 cases and 28 included equal or less than 5 cases. Analysis of the papers revealed that periapical implant lesion is classified according to evolution stages into acute (non-suppurated and suppurated) and subacute (or suppurated-fistulized). In the acute stage and in the subacute if there is no loss of implant stability, the correct treatment approach is implant periapical surgery. In the subacute stage associated with implant mobility the implant must be removed. Conclusions: Evidence on the subject is very limited, there are few studies with small sample, without homogeneity of criteria for diagnosing the disease and without design of scientific evidence. Currently etiology lacks consensus. The early diagnosis of periapical implant periapical lesions during the osseointegration phase and early treatment, will lead to a higher survival rate of implants treated, hence preventing the need for implant extraction (AU)

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Efficacy of different methods used for dry socket prevention and risk factor analysis: A systematic review

Background: Dry socket is one of the most common complications that develops after the extraction of a permanent tooth, and its prevention is more effective than its treatment. Objectives: Analyze the efficacy of different methods used in preventing dry socket in order to decrease its incidence after tooth extraction. Material and Methods: A Cochrane and PubMed-MEDLINE database search was conducted with the search terms 'dry socket', 'prevention', 'risk factors', 'alveolar osteitis' and 'fibrynolitic alveolitis', both individually and using the Boolean operator 'AND'. The inclusion criteria were: clinical studies including at least 30 patients, articles published from 2005 to 2015 and written in English. The exclusion criteria were case reports and nonhuman studies. Results: 30 publications were selected from a total of 250. Six of the 30 were excluded after reading the full text. The final review included 24 articles: 9 prospective studies, 2 retrospective studies and 13 clinical trials. They were stratified according to their level of scientific evidence using SIGN criteria (Scottish Intercollegiate Guidelines Network). Conclusions: All treatments included in the review were aimed at decreasing the incidence of dry socket. Locally administering chlorhexidine or applying platelet-rich plasma reduces the likelihood of developing this complication. Antibiotic prescription does not avoid postoperative complications after lower third molar surgery. With regard to risk factors, all of the articles selected suggest that patient age, history of previous infection and the difficulty of the extraction are the most common predisposing factors for developing dry socket. There is no consensus that smoking, gender or menstrual cycles are risk factors. Taking the scientific quality of the articles evaluated into account, a level B recommendation has been given for the proposed-procedures in the prevention of dry socket (AU)

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Clinical Evaluation of Root End Resection Bevel in Periapical Surgery.

Root end resections play an important role in the success of periapical surgery. Beveling of the root end resections can vary significantly depending on the surgical technique, the root and canal morphology. The intention of this article was to clinically assess the root resections bevels and to estimate their relation to applied periapical surgeries. A prospective clinical study consisted of sixty periapical surgeries performed on teeth with chronic periapical lesions. Thirty periapical surgeries were performed in a conventional manner, while thirty were contemporary ultrasonic surgeries. Following the completion of strictly planned and performed intraoperative procedures, the resection bevels were assessed. To obtain the real bevel angles a compass was used. Root resections were significantly less beveled in all teeth operated with contemporary ultrasonic surgery, with mean values between 2.1° to 7.8°. The number of roots and their dilacerations didn't influence the root resection bevel. For comparison, root resections were significantly beveled in all conventionally operated teeth, with mean values of 46°. Due to the technical limitations of the conventional periapical surgery, mandibular premolars were exclusively operated with ultrasonic periapical surgery, with mean values of resection bevel not exceeding 20.7°. Significantly lesser resection bevel associated with ultrasonic periapical surgery contributes to root preservation and favorable surgical outcome.

Periapical Microsurgery: The Effects of Locally Injected Dexamethasone on Pain, Swelling, Bruising, and Wound Healing.

INTRODUCTION: The purpose of this prospective, double-blind, randomized clinical trial was to evaluate the postoperative healing of endodontic periapical microsurgery after local administration of dexamethasone. METHODS: Sixty patients were divided into 2 groups. The dexamethasone group received a single local submucosal injection of 4 mg dexamethasone, and the placebo group received a submucosal injection of saline solution at the conclusion of standardized periapical microsurgery. Acetaminophen and hydrocodone/acetaminophen were prescribed for pain relief. A Likert-like 6-point scale was used for self-evaluation of pain, bruising, swelling, and wound healing at 24, 48, 72, 96 hours and at 1 week. The number of tablets taken was registered. Data were analyzed using the chi-square and Fisher exact tests at a significance level of P < .05. RESULTS: No improvements in pain, bruising, and wound healing were registered at any time interval. No difference was found in the number of tablets taken for pain relief. Subjects who received the dexamethasone injection reported less swelling 24 hours after periapical microsurgery (P < .05) but showed no significant benefit for the longer follow-up periods. CONCLUSIONS: This study shows that a 4-mg dose of dexamethasone administered through a local submucosal injection after periapical microsurgery has minimal impact on pain, bruising, and apparent wound healing at any time over a 7-day interval, and the impact on swelling seems limited.

[Endodontic re-treatment or apical surgery, is an evidence-based choice possible?]. / Endodontische herbehandeling of apexresectie: is een evidencebased keuze mogelijk?

Treatment of a recurrence after an initial endodontic treatment can consist of endodontic re-treatment or apical surgery. The literature reports comparable success rates for these two options. However, randomised controlled trials that are truly comparable to each other are unavailable as a result of which comparison and an informed choice are not really possible. In addition to the treatment outcome, consideration also has to be given to cost-effectiveness and other patient-related factors, such as pain, swelling and medication. Regarding these considerations, too, little reliable information can be found in the literature. Moreover, factors relating to insurance play an important role in the Netherlands, where only apical surgery is covered by the basic healthcare insurance. In conclusion, all of these factors should be carefully considered before proceeding to an individual treatment strategy.

Radiographic and histological evaluation of persistent periapical lesions associated with endodontic failures after apical microsurgery.

AIM: To determine the histology of persistent periapical lesions associated with nonsurgical endodontic treatment failures and to compare radiographically the sizes of periapical lesions and the presence or absence of the radiopaque lamina with the histological findings. METHODOLOGY: Ninety-three anterior teeth designated for apical microsurgery were included in the study. After taking standard radiographs of all cases using the parallel technique, the films were scanned and evaluated for the size of periapical radiolucent lesions and the presence or absence of radiopaque lamina by two calibrated observers. Biopsy specimens were obtained during apical microsurgery and examined under light microscopy by oral pathologists. Histological analysis established diagnoses of granuloma, cyst, abscess and scar tissue. Interobserver agreement was evaluated by the kappa test, and the relationship between histological diagnosis and lesion size was analysed by the Pearson's chi-square test. RESULTS: The 93 specimens consisted of 72% periradicular granulomas; 21.5% radicular cysts, including two keratocysts; 4.3% abscesses; and 2.2% scar tissue. Cystic prevalence increased as the size of the periapical lesion increased; however, there was no correlation between the presence of a radiopaque lamina and histological diagnosis of cyst. CONCLUSIONS: Neither radiographic size nor presence of an associated radiopaque line alone was sufficient to determine the type of lesion. Histological examination is required in order to reach to a definitive diagnosis.

Accessory mental foramina and nerves: Application to periodontal, periapical, and implant surgery.

Recent studies investigating accessory mental foramina using developments in diagnostic imaging have primarily defined the morphology of the foramina; however, few studies have described the structures passing through them. Additional clinical knowledge of the foramina is therefore required for preoperative diagnosis prior to surgery, including implant, periodontal and periapical surgery. In this study, we investigated the accessory mental foramina and the associated nerves and arteries in donated cadaveric mandibles using anatomical and radiological observation methods. We examined 63 mandibles with overlying soft tissue by cone-beam computed tomography and noted the existence of the accessory mental foramina. Mandibles with accessory mental foramina were subsequently analyzed. Additionally, the neurovascular bundles passing through these foramina were dissected using anatomical methods.The incidence of accessory mental foramina was 14.3%. The larger foramina tended to be located anteriorly or superiorly and proximal to the mental foramen, while the smaller foramina tended to be located posterosuperiorly and distal to the mental foramen. The mental foramen ipsilateral to the accessory mental foramen was smaller than the one contralateral to it. The comparatively distant and large accessory mental foramen included an artery.This study elucidated the relationship between accessory mental foramina and the associated nerves and arteries. We believe that the results will contribute to the clinical dentistry field.

Agreement between 2D and 3D radiographic outcome assessment one year after periapical surgery.

AIM: To compare 2D with 3D radiography in assessing the treatment outcome 1 year after periapical surgery. METHODOLOGY: In this prospective study, periapical radiographs (PA) and cone beam computed tomography (CBCT) were performed 1 year after periapical surgery. Three calibrated observers independently evaluated the radiographs for the presence and type of periapical radiolucencies. Ratings in PA were compared to those in bucco-lingual and mesio-distal CBCT images (coronal and sagittal planes), and the ratings of the latter two were also compared between each other. Further, maximum size diameters of radiolucencies were measured on CBCT scans, and the calculated means were correlated with the types of radiolucency. Statistical analysis was completed using Friedman rank sum tests, the Wilcoxon signed rank test and the Pearson correlation coefficient. RESULTS: A total of 61 roots in 54 patients were eligible for the final assessment. On average, the intra-observer ratings were identical in 59.6% when comparing PA and CBCT (kappa 0.112 to 0.192). A very high intra-observer agreement (93.4%) was noted when comparing bucco-lingual and mesio-distal CBCT ratings (kappa 0.797 to 1). Interobserver agreement was higher for PA (68.8%) than for CBCT (bucco-lingual 45.9%, mesio-distal 47.5%), but without reaching significant differences. The calculated mean size of persistent radiolucencies in CBCT scans correlated well with the assigned types of radiolucency. CONCLUSION: CBCT images showed in nearly a third of the evaluated cases a worse situation than PA. There is a need to define criteria to assess the 'radiographic healing' in CBCT following periapical surgery.

Prognostic factors on periapical surgery: a systematic review

BACKGROUND: Analyze the most important prognostic factors when performing periapical surgery and compare the success rates of distinct authors. INTRODUCTION: Periapical surgery is an approach to treat non-healing periapical lesions and it should be viewed as an extension of endodontic treatment and not as a separate entity. MATERIAL AND METHODS: A search of articles published in Cochrane, PubMed (MEDLINE) and Scopus was conducted with the key words "prognostic factors", "prognosis", "periapical surgery", "endodontic surgery" and "surgical endodontic treatment". The inclusion criteria were articles including at least 10 patients, published in English, for the last 10 years. The exclusion criteria were nonhuman studies and case reports. RESULTS: 33 articles were selected from 321 initially found. Ten articles from 33 were excluded and finally the systematic review included 23 articles: 1 metaanalysis, 1 systematic review, 2 randomized clinical trials, 6 reviews, 12 prospective studies and 1 retrospective study. They were stratified according to their level of scientific evidence using the SORT criteria. CONCLUSIONS: Factors associated with a better outcome of periapical surgery are patients ≤45 years old, upper anterior or premolar teeth, ≤10 sized lesions, non cystic lesions, absence of preoperative signs and symptoms, lesions without periodontal involvement, teeth with an adequate root-filling length, MTA as root-end filling material, uniradicular teeth, absence of perforating lesions, apical resection < 3 mm, teeth not associated to an oroantral fistula and teeth with only one periapical surgery

Current Concepts of Periapical Surgery.

Preoperative decision-making is vital to determine potential success of periapical surgery. Adequate exposure of the root apical region is best approached via a sulcular-type incision. Surgical procedures include resection of 2 to 3 mm of the apical portion along with root end preparation and seal. The surgeon must decide if submission of periapical tissues to pathology is indicated.

Análisis comparativo in vitro de la capacidad de sellado marginal en cavidades a retro del MTA y del cemento de óxido de cinc-eugenol reforzado / In vitro analysis and comparison of the apical sealing capability of MTA and a reinforced zinc oxide-eugenol cement

Objetivo: El objetivo de este estudio consiste en comparar la capacidad de sellado apical de dos materiales empleados en la obturación de cavidades a retro en cirugía periapical: MTA y un cemento de óxido de cinc-eugenol reforzado (Super EBA(R)). Material y métodos: Se llevó a cabo un estudio in vitro con dientes unirradiculares extraídos, a fin de evaluar la capacidad de sellado apical de dos materiales empleados como material de obturación en cavidades a retro: cemento de óxido de cinc reforzado (Súper EBA(R)) (n = 30) y MTA (n = 30). Además, se creó un grupo control negativo (n = 5) y otro positivo (n = 5). Las muestras procesadas fueron sumergidas en tinta China y posteriormente diafanizadas. Tras secar las muestras, se cuantificó el grado de filtración (mm) mediante un software de análisis de imagen. Los resultados fueron analizados utilizando el test de la t de Student, empleando el programa SPSS versión 20.0. Un valor de p ≤ 0,05 fue considerado significativo. Resultados: El 6,6% y el 10% de las muestras obturadas con MTA o con Súper EBA(R), respectivamente, sufrieron una filtración completa. Estas referencias revelaron que el grado de filtración no depende del material empleado (p = 0,133). Conclusión: No existen diferencias respecto al grado de filtración entre ambos materiales empleados en el sellado retrocavitario

Objectives: The aim of this study was to compare the apical sealing capabilities of the mineral trioxide aggregate (MTA) and of the reinforced zinc oxide-eugenol cement Super EBA(R). Material and methods. An in vitro study was carried out using extracted single-rooted teeth samples. Two materials were tested as root-end filling materials: a reinforced zinc oxide-eugenol cement (Super EBA(R)) (n = 30) and mineral trioxide aggregate (MTA) (n = 30). Another two groups were created as negative (n = 5) and positive (n = 5) control groups. The samples were put in Chinese ink and then diafanizated. Once dried, the level of leakage (mm) was measured by an image software program. The results were analysed using Student's t-test, using the SPSS version 20.0. Differences with p value lower or equal 0.05 were considered significant. Results: Mean filtration in MTA group was 0.77 ± 1.006, whereas in the SuperEba group it was 1.20 ± 1.186 (p = 0.133). Complete leakage was found in 6.6% of the samples filled with MTA and in 10% of those filled with Super EBA(R) (p = 0.133). The level of leakage was not influenced by the material used and null hypothesis can be accepted. Conclusion: Both type of root-end filling materials analysed in this research, are indicated for sealing the retropreparation, without differences in the leakage

Treatment of large apical lesions with mucosal fenestration: a clinical study with long-term evaluation.

INTRODUCTION: Mucosal fenestration at the root apex may compromise the treatment results of periradicular surgery from exposing the surgical wound to the oral environment. The purpose of this study was to evaluate the long-term outcomes of periapical lesions with mucosal fenestrations treated by guided tissue regeneration (GTR) combined with the management of soft tissue defects. METHODS: Five patients with mucosal fenestration and large periapical lesions were treated by endodontic surgeries and periodontal regenerative procedures during 1999 to 2006. The barrier membranes and osseous grafts were placed over the periapical defects after root end resection and retrograde filling. The mucosal openings in all cases were sutured, whereas a connective tissue graft was placed before repositioning the flap in 2 cases. RESULTS: The cases involving connective tissue grafting showed complete soft tissue coverage, whereas 2 of the 3 cases involving primary closure of fenestrations still had a small soft tissue opening that was further managed by placement of a connective tissue graft beneath in 1 case and direct suturing in the other case. After at least 6 years (72-160 months) of follow-up, all cases showed complete soft tissue and radiographic healing. CONCLUSIONS: Connective tissue grafting in combination with GTR therapy facilitated fenestration closure and ensured long-term success in the treatment of a large periapical bony defect with mucosal fenestration.

Materials and prognostic factors of bone regeneration in periapical surgery: A systematic review

OBJECTIVES: Analyse the effectiveness of different materials and techniques used in guided tissue regeneration (GTR) applied in periapical surgery, comparing the success rate obtained in 4-wall defects and in through-and-through bone lesions as well as to establish prognostic factors. MATERIAL AND METHODS: A Cochrane, PubMed-MEDLINE and Scopus database search (October 2012 to March 2013) was conducted with the search terms "periapical surgery", "surgical endodontic treatment", "guided tissue regeneration", "bone regeneration", "bone grafts", "barrier membranes" and "periapical lesions" individually and next, using the Boolean operator "AND". The inclusion criteria were the use of GTR (bone graft and/or membrane barrier), clinical studies including at least 10 patients, 10 years aged articles published in English or French. The exclusion criteria were case reports and nonhuman studies. RESULTS: 34 publications were selected from a total of 483. 9 of the 34 were excluded. Finally, the systematic review included 25 articles: 2 metaanalysis, 8 reviews, 13 prospective studies and 2 retrospective studies. They were stratified according to their level of scientific evidence using the SORT criteria. The 4-wall periapical and through-and-through lesions improve more their prognosis by combining bone grafts and barrier membranes than using these materials exclusively, respect to the control groups. The results show lower failure rates in in 4-wall le-sions than in through-and-through lesions using GTR. CONCLUSIONS: The combined GTR technique (filling material and membranes) obtains a greater success rate both in 4-wall lesions and in through-and-through lesions, respect to the control groups. The use of regeneration materials seems to be more necessary in through-and-through lesions, > 5mm lesions, lower teeth and apicomarginal lesions as they have the worst healing prognosis. In function of the articles scientific quality, a type B recommendation is given in favour to the use of GTR in association of periapical surgery in case of 4-wall and through-and-through lesions

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Root reconstructed with mineral trioxide aggregate and guided tissue regeneration in apical surgery: a 5-year follow-up.

Apical surgery should be considered as the last treatment option and employed when conventional endodontic treatment does not provide the expected result. In teeth undergoing apical surgery, the type of retrograde filling material is one of the factors interfering with the repair of periapical tissues. The material in intimate contact with the periapical tissues plays a fundamental role in the repair process. Several materials have been studied and indicated for use in apical surgery procedures, but the mineral trioxide aggregate (MTA) is still the most frequently used one. Guided tissue regeneration (GTR) techniques have been proposed as an adjunct to apical surgery to enhance bone healing. Here is reported a clinical case in which apical surgery was performed in conjunction with MTA-based root reconstruction of the maxillary right second incisor. After the apical surgery, a root-end cavity was prepared at the vestibular face of the involved tooth and filled with MTA. A bovine bone graft and a cortical collagen membrane were placed on the bone defect. After 5 years, clinical and radiographic assessments showed that the treatment was successful. It may be concluded that MTA presents favorable characteristics in adverse conditions and can be used in conjunction with GTR in cases involving root reconstruction.

Root Reconstructed with Mineral Trioxide Aggregate and Guided Tissue Regeneration in Apical Surgery: A 5-year Follow-up

Apical surgery should be considered as the last treatment option and employed when conventional endodontic treatment does not provide the expected result. In teeth undergoing apical surgery, the type of retrograde filling material is one of the factors interfering with the repair of periapical tissues. The material in intimate contact with the periapical tissues plays a fundamental role in the repair process. Several materials have been studied and indicated for use in apical surgery procedures, but the mineral trioxide aggregate (MTA) is still the most frequently used one. Guided tissue regeneration (GTR) techniques have been proposed as an adjunct to apical surgery to enhance bone healing. Here is reported a clinical case in which apical surgery was performed in conjunction with MTA-based root reconstruction of the maxillary right second incisor. After the apical surgery, a root-end cavity was prepared at the vestibular face of the involved tooth and filled with MTA. A bovine bone graft and a cortical collagen membrane were placed on the bone defect. After 5 years, clinical and radiographic assessments showed that the treatment was successful. It may be concluded that MTA presents favorable characteristics in adverse conditions and can be used in conjunction with GTR in cases involving root reconstruction.

A cirurgia apical deve ser considerada como a última opção de tratamento, e realizada quando o tratamento endodôntico convencional não proporciona o resultado esperado. Em dentes submetidos à cirurgia apical, o tipo de material retro-obturador é um dos fatores que interferem no reparo dos tecidos periapicais. O material em íntimo contato com os tecidos periapicais desempenha um papel fundamental no processo de reparo. Vários materiais têm sido estudados e indicados para o uso em procedimentos de cirurgias apicais, entretanto o agregado de trióxido mineral (MTA) ainda é o mais frequentemente utilizado. A regeneração tecidual guiada (GTR) tem sido proposta como um auxiliar na cirurgia apical para melhorar a formação óssea. Aqui é relatado um caso clínico em que a cirurgia apical foi realizada em conjunto com a reconstrução radicular do incisivo lateral superior esquerdo com MTA. Após a cirurgia apical, foi preparada uma retro-cavidade na parede vestibular e o dente envolvido foi obturado com MTA. Um enxerto de osso bovino e uma membrana de colágeno cortical foram colocados no defeito ósseo. Após 5 anos, avaliações clínica e radiográfica mostram que o tratamento foi bem sucedido. Pode-se concluir que o MTA apresenta características favoráveis em condições adversas e que pode ser usado em conjunto com GTR em casos envolvendo reconstrução radicular.

Pain and swelling after periapical surgery related to the hemostatic agent used: Anesthetic solution with vasoconstrictor or aluminum chloride

Objective: To assess pain and swelling in the first 7 days after periapical surgery and their relationship with the agent used for bleeding control. Study Design: A prospective study was conducted between October 2006 and March 2009. Patients subjected to root surgery, who completed the questionnaire and who consented to the postoperative instructions were included in the study. The subjects were divided into two groups according to the hemostatic agent used: A) gauze impregnated with anesthetic solution with vasoconstrictor; or B) aluminum chloride. The patients were administered a questionnaire, and were asked to record the severity of their pain and swelling on a plain horizontal visual analog scale (VAS). Data were recorded by the patients on the first 7 postoperative days. In addition, the patients were asked to record analgesic consumption. Results: A total of 76 questionnaires (34 in group A and 42 in group B) were taken to be correctly completed. Pain was reported to be most intense two hours after surgery. At this point 52.6% of the patients had no pain. Seventy-five percent of the patients consumed analgesics in the first 24 hours. There were no significant differences between the two groups in terms of the intensity of pain or in the consumption of analgesics. Swelling reached its maximum peak on the second day; at this point, 60.6% of the patients suffered mild or moderate swelling. The Expasyl™ group showed significantly greater swelling than the gauzes group. Conclusion: The type of hemostatic agent used did not influence either the degree of pain or the need for analgesia among the patients in this study. However, the patients belonging to the Expasyl™ group suffered greater swelling than the patients treated with gauzes impregnated with anesthetic solution with vasoconstrictor (AU)

Treatment of through-and-through bone lesion using autologous growth factors and xenogeneic bone graft: a case report.

BACKGROUND: This pilot case study aimed at evaluating the possibility of achieving optimal hard and soft tissue regeneration using plasma rich in growth factors (PRGF) and anorganic bovine bone (ABB) for the surgical treatment of a large through-and-through periapical bone lesion. CASE REPORT: Maxillary incisors of a patient with through-and-through periapical lesion of endodontic origin were treated using modern endodontic surgical technique with the adjunct of PRGF. The PRGF clot was positioned over the palatal side of the lesion while the remaining bone defect was grafted with PRGF and ABB. A collagen membrane embedded with plasma very rich in growth factors covered the graft. Post-operative pain and swelling were negligible, and soft tissue healing was very fast. One-year clinical and radiographic outcome showed complete healing and functionality. DISCUSSION: The addition of PRGF to ABB could improve the regenerative process, reducing postoperative symptoms and resulting in a fast and predictable hard and soft tissue healing.

A prospective clinical study of polycarboxylate cement in periapical surgery.

OBJECTIVE: To evaluate the clinical efficacy of polycarboxylate cement as retrograde filling material. DESIGN: A prospective clinical study was made of 25 patients subjected to periapical surgery with ultrasound and magnifying loupes, in which polycarboxylate cement was used as retrograde filling material. Measurements were made of the area and diameter of the lesions pre- and postoperatively, and 6 and 12 months after the operation. The apical resection and retrograde filling areas were also measured, and the prognosis following surgery was recorded. RESULTS: A total of 23 patients with 31 apicoectomized teeth were studied (2 patients being lost to follow-up). The mean area of the periapical lesions before surgery was 52.25 mm2, with a mean major diameter of 6.1 mm and a mean lesser diameter of 4.8 mm. The success rate after 12 months was 54.7%, according to the criteria of Von Arx and Kurt. The prognosis was poorer in females, in larger lesions, and in cases with larger retrograde filling areas. CONCLUSIONS: Polycarboxylate cement offers good results, with important bone regeneration after periapical surgery.